Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
Blog Article
Our new Clear+ tissue clearing method is the sole strategy that delipidates samples without modify in morphology and with nominal impact on structural integrity.
Megatome can be a vibrating microtome built to portion a wide selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform floor profile, together with negligible tissue damage and information loss.
Antibodies might consider weeks to diffuse via only a few millimeters of tissue, having a steep labeling gradient from surface to core.
Megatome is designed for accuracy: the blade vibrates at a higher frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Command system.
SE makes use of a rotational electric field to disperse really electromobile molecules (which include antibodies or surfactant micelles) in the course of a porous sample with no detrimental electrically charged structures throughout the tissue. This allows two-4 day clearing of intact organs,
Our preformulated EasyIndex Answer raises and homogenize the refractive index of delipidated tissue samples, rendering them fully clear. This permits mild penetration into the sample and makes sure the acquisition of significant-resolution, in-emphasis megatomi.com picture data.
Megatome is actually a novel microtome that allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue damage and data decline.
It’s time and energy to upgrade your microtome to Megatome. With exact large-frequency slicing for an unmatched range of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for various applications.
Completely delipidate full mouse brains or comparably sized samples in just one working day with SmartBatch+, or in one 7 days with our passive clearing kit.
Docset creation involves at minimum two solutions: the title of your docset and The placement of the Javadoc documents to include inside the docset.
This can make a docset named Sample in the current Listing. Docset generation may be tailored with optional arguments:
Protect avoids the variability of hydrogel embedding and the information reduction from PFA preservation, safeguarding specimens for various rounds of processing.
--displayName: Will established the identify as shown in Dash. That is helpful in the event you produce a docset with title SampleProject but Display screen name Sample Undertaking alternatively. This location will default to the value of --name if omitted.
Our novel Defend tissue preservation procedure forms intramolecular bonds working with polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.